Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Skin Diseases and Disorders

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Gillespie syndrome caused by a novel <i>ITPR1</i> gene variant: a phenotype-genotype correlation.

Ophthalmic genetics·2026

Same author

Association of Autosomal Dominant Snowflake Vitreoretinal Degeneration with Retinoschisis.

Ophthalmology science·2026

Same author

Gelatinous drop-like amyloid in FOXC2 distichiasis syndrome: a case report.

BMC ophthalmology·2026

Same author

Lipemia retinalis: a case study of a rare finding in pediatric retina secondary to diabetes.

Canadian journal of ophthalmology. Journal canadien d'ophtalmologie·2026

Same author

Eye care adherence in pediatric and elderly: Understanding and addressing the challenges.

Progress in retinal and eye research·2026

Same author

Bilateral juvenile-onset cataracts associated with <i>GCNT2</i> variants.

Ophthalmic genetics·2026

Search research articles

Related Experiment Video

Updated: Aug 2, 2025

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Thygeson's superficial punctate keratitis in children.

Meghal Gagrani^1,2, Elizabeth A Conner^1,2, Hannah Scanga^1,2

¹UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, USA.

Eye (London, England)

|April 21, 2023

Summary

Thygesons

More Related Videos

Iris Fixation via External Pentagram Suturing

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

Related Experiment Videos

Last Updated: Aug 2, 2025

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Iris Fixation via External Pentagram Suturing

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts

Published on: September 20, 2018

Area of Science:

Ophthalmology
Corneal Diseases

Background:

Thygesons' superficial punctate keratitis (TSPK) is a rare corneal condition.
Management strategies in pediatric TSPK require further elucidation.

Purpose of the Study:

To describe the first case series of pediatric Thygesons' superficial punctate keratitis (TSPK).
To evaluate management outcomes, including visual acuity and treatment response.
To assess the impact of steroid and cyclosporine use on total steroid exposure.

Main Methods:

Retrospective chart review of pediatric TSPK cases from 2012-2021.
Assessment of clinical signs, symptoms, diagnosis, and treatment interventions.
Evaluation of visual acuity, treatment response, and steroid exposure.

Main Results:

Fifteen children with TSPK were included, all with bilateral disease.
Topical fluorometholone (FML) showed an 80% initial response rate.
Cyclosporine 0.05% use significantly reduced total weekly steroid exposure (p < 0.05).

Conclusions:

Pediatric TSPK responds well to steroids but frequently recurs, requiring slow tapering.
Non-response to steroids warrants diagnostic re-evaluation.
Topical cyclosporine 0.05% is effective in reducing steroid dependency in TSPK management.