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Murine Ileocolic Bowel Resection with Primary Anastomosis
Published on: October 29, 2014
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Immune mediated colitis: a surgical perspective.
Khang Duy Ricky Le1,2,3, Kay Tai Choy4, Sara Roth5,6,7
1Department of General Surgical Specialties, The Royal Melbourne Hospital, Melbourne, Victoria, Australia.
ANZ Journal of Surgery
|April 24, 2023
Summary
This review highlights the crucial role of surgical specialties in managing immune-mediated colitis, an adverse event of cancer immunotherapy. Surgeons are increasingly needed for prompt diagnosis and multidisciplinary care of this condition.
Area of Science:
- Oncology
- Gastroenterology
- Surgical Specialties
Background:
- Immune-mediated colitis is a significant adverse event associated with cancer immunotherapy.
- Current management often mirrors inflammatory bowel disease protocols, primarily involving medical specialties.
Purpose of the Study:
- To review and summarize current literature on immune-mediated colitis treatment.
- To explore the role of surgical specialties in the management of immune-mediated colitis.
Main Methods:
- A narrative review of relevant literature was conducted.
- Literature search performed using Medline, EMBASE, and Cochrane Central databases.
Main Results:
- Diagnosis and treatment guidelines for immune-mediated colitis are guided by oncology and gastroenterology.
- Surgical expertise is essential for diagnosis and managing complications of immune-mediated colitis.
Conclusions:
- Surgical involvement is critical for comprehensive immune-mediated colitis management.
- Surgeons need to be familiar with multidisciplinary approaches for prompt diagnosis and treatment.
- Enhanced collaboration between surgical and medical specialties is necessary for optimal patient care.
Keywords:
checkpoint inhibitor induced colitischeckpoint inhibitorscoloncytotoxic T-lymphocyte associated antigen 4immune checkpoint inhibitorsimmune mediated colitisimmune related adverse eventsimmune therapyimmunotherapyimmunotherapy induced colitisprogrammed cell death protein 1programmed death ligand 1
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