Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Immunodeficiency Diseases01:25

Immunodeficiency Diseases

1.1K
Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency...
1.1K
Pulmonary Tuberculosis I01:29

Pulmonary Tuberculosis I

294
Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
294
Transmission-based Precautions II: Airborne and Protective Environment01:25

Transmission-based Precautions II: Airborne and Protective Environment

1.3K
Transmission-based precautions are for patients infected or suspected to be infected (or colonized) with organisms posing a significant risk to others. The transmission precautions include airborne and protective environment precautions.
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...
1.3K
Pulmonary Tuberculosis IV01:26

Pulmonary Tuberculosis IV

184
Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
184
Development of Immunocompetence01:22

Development of Immunocompetence

381
The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
381

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Aurora-Associated Geomagnetic Activity and Health: A Review With Focus on Neurological Implications.

GeoHealth·2026
Same author

Curcumin-loaded nanocarriers for dermatological applications: current advances and biomedical implications.

EXCLI journal·2026
Same author

Exploring the Cellular and Molecular Mechanisms Underlying Alzheimer's Disease Utilizing Cerebral Organoids Derived from Patient-specific Induced Pluripotent Stem Cells (iPSCs): A Review with Implications for Surgical Interventions.

Current neuropharmacology·2026
Same author

Targeting Type 2 and Non-type 2 Asthma: Emerging Biologics and Personalized Strategies.

Current allergy and asthma reports·2026
Same author

Smart Nanostructures in Oncology: Revolutionising Drug Delivery and Diagnostics.

Current pharmaceutical design·2026
Same author

Viral orchitis and male infertility: A comprehensive review of pathogenic mechanisms and outcomes.

Journal of reproductive immunology·2026

Related Experiment Video

Updated: Aug 1, 2025

Novel Protocol for Generating Physiologic Immunogenic Dendritic Cells
12:08

Novel Protocol for Generating Physiologic Immunogenic Dendritic Cells

Published on: May 17, 2019

9.3K

Monkeypox (mpox) in immunosuppressed patients.

Sirwan Khalid Ahmed1, Mona Gamal Mohamed2, Eman Abdelaziz Dabou2

  • 1Department of Pediatrics, Rania Pediatric & Maternity Teaching Hospital, Rania, Sulaymaniyah, Kurdistan Region, 46012, Iraq.

F1000Research
|April 25, 2023
PubMed
Summary
This summary is machine-generated.

Mpox (formerly monkeypox) poses a severe risk to immunocompromised individuals, particularly those with advanced Human Immunodeficiency virus (HIV). Further research is crucial for effective mpox treatment and prevention in vulnerable populations.

Keywords:
autoimmune diseasecontrolhuman immunodeficiency virusimmunocompromised patientsmanagementmonkeypoxprevention

More Related Videos

Merkel Cell Polyomavirus Infection and Detection
13:45

Merkel Cell Polyomavirus Infection and Detection

Published on: February 7, 2019

10.0K
Vaccinia Reporter Viruses for Quantifying Viral Function at All Stages of Gene Expression
10:48

Vaccinia Reporter Viruses for Quantifying Viral Function at All Stages of Gene Expression

Published on: May 15, 2014

11.5K

Related Experiment Videos

Last Updated: Aug 1, 2025

Novel Protocol for Generating Physiologic Immunogenic Dendritic Cells
12:08

Novel Protocol for Generating Physiologic Immunogenic Dendritic Cells

Published on: May 17, 2019

9.3K
Merkel Cell Polyomavirus Infection and Detection
13:45

Merkel Cell Polyomavirus Infection and Detection

Published on: February 7, 2019

10.0K
Vaccinia Reporter Viruses for Quantifying Viral Function at All Stages of Gene Expression
10:48

Vaccinia Reporter Viruses for Quantifying Viral Function at All Stages of Gene Expression

Published on: May 15, 2014

11.5K

Area of Science:

  • Infectious Diseases
  • Immunology
  • Public Health

Background:

  • Mpox (formerly monkeypox) declared a public health emergency in July 2022.
  • Immunocompromised individuals face higher risks of severe mpox and mortality.
  • Limited access to diagnostics, vaccines, and treatment in low-income countries exacerbates mpox risks.

Purpose of the Study:

  • To review the clinical presentation of mpox in immunocompromised patients.
  • To discuss available treatment options for mpox in immunocompromised individuals.
  • To outline current preventive guidelines for mpox in immunocompromised populations.

Main Methods:

  • Literature review of mpox clinical presentation.
  • Analysis of available mpox treatment strategies.
  • Synthesis of current mpox preventive guidelines for immunocompromised groups.

Main Results:

  • Severe mpox manifestations are disproportionately higher in individuals with Human Immunodeficiency virus (HIV) and low CD4 counts.
  • Immunocompromised patients exhibit a reduced ability to mount protective immune responses against mpox.
  • Continued emergence of mpox cases is expected, especially in regions with limited healthcare access and high HIV prevalence.

Conclusions:

  • Mpox presents a significant threat to immunocompromised individuals, necessitating tailored clinical management.
  • Urgent need for further research to establish optimal mpox treatment protocols for immunocompromised patients.
  • Enhanced diagnostic, therapeutic, and preventive strategies are essential for controlling mpox in vulnerable populations worldwide.