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A case of Co-infection COVID-19 and influenza with psychotic symptoms

Maryam Valikhani1, Arghavan Feyzmanesh2, Salman Daliri3

  • 1Imam Hossein Hospital, Shahroud University of Medical Sciences, Shahroud, Iran.

Heliyon
|April 24, 2023
PubMed

Insights

This case study reports a rare instance of co-infection with COVID-19 and influenza in a teenager presenting with severe psychotic symptoms. Prompt treatment led to the patient's full recovery.

Area of Science:

  • Infectious Diseases
  • Neurology
  • Psychiatry

Background:

  • Coronavirus disease 2019 (COVID-19) is a global pandemic with diverse clinical presentations.
  • Co-infections with other pathogens can complicate COVID-19, potentially worsening patient outcomes.
  • The neurological and psychiatric manifestations of COVID-19 co-infections require further investigation.

Observation:

  • A 16-year-old male presented with fever, chills, cough, body aches, headache, seizures, and delirium.
  • Laboratory tests confirmed co-infection with both COVID-19 and influenza.
  • Initial laboratory variables and imaging showed no significant abnormalities.

Findings:

  • The patient exhibited acute psychotic symptoms, including delirium and seizures, alongside typical respiratory symptoms.
  • Reverse transcription-polymerase chain reaction (RT-PCR) confirmed the presence of both SARS-CoV-2 and influenza viruses.
  • Despite the severity of psychotic symptoms, standard laboratory markers remained unremarkable.

Implications:

  • This case highlights the potential for severe neuropsychiatric complications in patients with dual COVID-19 and influenza infections.
  • Early diagnosis and management of co-infections are crucial for favorable outcomes, even with unusual presentations.
  • Further research is warranted to understand the mechanisms underlying psychotic symptoms in viral co-infections.

Keywords:
COVID-19Co-infectionCoronavirusInfluenzaPsychotic symptoms

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