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Bilateral Upper Extremity Superficial Venous Thrombosis and Altered Mental Status as Initial Manifestations of
Milad Rezvani1, Mahdi Naeiji1, Hasan Maghsoudifar1
1Student Research Committee, School of Medicine Shahroud University of Medical Sciences Shahroud Iran.
Clinical Case Reports
|August 23, 2026
Abstract:
A 72-year-old woman with fever, confusion, and upper extremity superficial venous thrombosis was admitted. Despite screening for infectious, neurologic, and autoimmune causes, no diagnosis was established. Generalized lymphadenopathy was found afterwards. An excised lymph node biopsy with immunohistochemical analysis revealed aggressive B-cell lymphoma.
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Disorders of Leukocytes
Leukocyte disorders can lead to either leukopenia, characterized by an abnormally low leukocyte count, or leukocytosis, marked by a very high leukocyte number.
Leukopenia may result from bone marrow disorders, autoimmune diseases, and infectious diseases. For example, conditions such as multiple myeloma and aplastic anemia can impair the bone marrow's ability to produce adequate leukocytes. Similarly, autoimmune diseases like lupus and viral infections such as HIV can prompt the immune system...
Leukopenia may result from bone marrow disorders, autoimmune diseases, and infectious diseases. For example, conditions such as multiple myeloma and aplastic anemia can impair the bone marrow's ability to produce adequate leukocytes. Similarly, autoimmune diseases like lupus and viral infections such as HIV can prompt the immune system...
Primary Lymphoid Organs
Primary lymphoid organs are pivotal in the formation, development, and maturation of lymphocytes, the white blood cells that serve as the backbone of our immune system. This crucial function underscores their fundamental role in maintaining our overall health and immunity. The two primary lymphoid organs of prime importance are the red bone marrow and the thymus.
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...