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Eye of the Tiger: Looking Beyond Neurodegeneration with Brain Iron Accumulation Disorders
Prajnya Ranganath1, Mallikarjun Patil1
1Department of Medical Genetics, Nizam's Institute of Medical Sciences, Hyderabad, Telangana, India.
Abstract:
The "eye-of-the-tiger" sign in brain magnetic resonance imaging (MRI) is typically associated with neurodegeneration with brain iron accumulation disorders, especially pantothenate kinase-associated neurodegeneration. However, very similar neuroimaging findings may be seen in other neurodegenerative disorders involving the basal ganglia. We report here a patient with fucosidosis who had MRI brain findings closely resembling the "eye-of-the-tiger" sign.
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