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Microscopy-based Assays for High-throughput Screening of Host Factors Involved in Brucella Infection of Hela Cells
Published on: August 5, 2016
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Neurobrucellosis
Cristiane N Soares1, Marcus Tulius T da Silva2, Marco Antonio Lima3
1Infectious Diseases Department (DIP 1) - Hospital Federal dos Servidores do Estado.
Current Opinion in Infectious Diseases
|April 24, 2023
Summary
Neurobrucellosis, a complication of brucellosis affecting 4% of patients, presents with diverse neurological symptoms and can be misdiagnosed. Early recognition and antibiotic treatment are crucial for patient recovery and disease control.
Area of Science:
- Infectious Diseases
- Neurology
- Zoonosis Research
Background:
- Brucellosis is a prevalent global zoonotic disease affecting approximately 500,000 individuals annually.
- Neurobrucellosis, a neurological complication, occurs in about 4% of brucellosis cases and is characterized by heterogeneous clinical presentations.
- The non-specific symptoms of neurobrucellosis often lead to misdiagnosis with other infections.
Conclusions:
- Neurobrucellosis is an often unrecognized and underreported global health concern.
- Understanding its epidemiology is vital for effective disease eradication in humans and control in animals.
- Prevention strategies focusing on occupational and food hygiene are essential for mitigating the spread of brucellosis and its neurological complications.
