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Withdrawal from Hemodialysis in a Patient with IgD Type Multiple Myeloma: A Case-based Review
Hiroki Iriyoshi1, Ken-Ei Sada1,2,3, Atsushi Miyauchi1
1Department of Internal Medicine, Kochi Prefectural Hata-Kenmin Hospital.
Abstract:
Several previous case reports have shown that patients with immunoglobulin D (IgD) multiple myeloma (MM) can be withdrawn from hemodialysis, however, the characteristics that can predict withdrawal in these patients have not yet been elucidated. A 57-year-old Japanese woman required hemodialysis because of renal dysfunction due to IgD-λ and Bence Jones protein-λ MM. Bortezomib-based chemotherapy nine days after admission led to her withdrawal from hemodialysis on Day 50. In our case-based review, younger age and early initiation of bortezomib-based chemotherapy emerged as possible predictors of successful hemodialysis withdrawal.
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