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Updated: Jun 20, 2026

09:45
Photodynamic Therapy with Blended Conducting Polymer/Fullerene Nanoparticle Photosensitizers
Published on: October 28, 2015
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Copper coordination-based conjugated polymer nanoparticles for synergistic photodynamic and chemodynamic therapy
Qiang Cheng1, Yuyan Li1, Wei Huang2
1College of Chemistry & Chemical Engineering, Central South University, Changsha, Hunan 410083, China. benhuawang@csu.edu.cn.
Abstract:
In this work, we presented a copper coordination-based conjugated polymer nanoparticle (PPE-Cu NPs) for synergistic PDT/CDT. Upon irradiation, PPE-Cu NPs exhibited good singlet oxygen generation capability (ΦΔ = 0.33). Meanwhile, PPE-Cu NPs were able to generate ˙OH in the presence of GSH and H2O2. Cellular experiments demonstrated that PPE-Cu NPs can serve as effective agents for synergistic PDT/CDT therapy.

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