Influence and predictive value of optional parameters in new-generation intraocular lens formulas
Jascha A Wendelstein1, Jan Rothbächer, Michael Heath
1From the Institut für Refraktive und Ophthalmochirurgie (IROC), Zurich, Switzerland (Wendelstein, Seiler); Department for Ophthalmology and Optometry, Kepler University Hospital GmbH, Linz, Austria (Wendelstein); Johannes Kepler University Linz, Medical Faculty, Linz, Austria (Wendelstein, Rothbächer); Institute of Experimental Ophthalmology, Saarland University, Homburg, Germany (Wendelstein, Langenbucher); Dean A. McGee Eye Institute/University of Oklahoma, Oklahoma City, Oklahoma (Heath, McDonald, Riaz); Augen-und Laserklinik, Castrop-Rauxel, Germany (Hoffmann); Great Lakes Eye Care, Saint Joseph, Michigan (Cooke); Department of Neurology and Ophthalmology, Michigan State University, College of Osteopathic Medicine, East Lansing, Michigan (Cooke).
Purpose:
To evaluate the accuracy of various variations of new-generation multivariate intraocular lens (IOL) power calculation using the Barrett Universal II, Castrop, Emmetropia Verifying Optical 2.0, Hill-Radial Basis Function 3.0, Kane, and PEARL-DGS formulas with and without optional biometric parameters.
Setting:
Tertiary care academic medical center.
Design:
Retrospective case series. Single-center study.
Methods:
Inclusion of patients after uneventful cataract surgery implanting AU00T0 IOLs. Data from one eye per patient were randomly included. Eyes with a corrected distance visual acuity worse than 0.1 logMAR were excluded. IOLCON-optimized constants were used for all formulas other than the Castrop formula. The outcome measures were prediction error (PE) and absolute prediction error (absPE) for the 6 study formulas.
Results:
251 eyes from 251 patients were assessed. Excluding lens thickness led to statistically significant differences in absPE in several formulas. Leaving out horizontal corneal diameter did not impact absPE in several formulas. Differences in PE offset were observed between the various formula variations.
Conclusions:
When using multivariate formulas with an A-constant, including certain optional parameters is vital for optimal refractive results. Formula variations excluding certain biometric parameters need specifically optimized constants and do not perform similarly when using the constant of the respective formula using all parameters.
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