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Optic Disc Measurements in Children by Optical Coherence Tomography
Hassan Hashemi1, Mehdi Khabazkhoob2, Samira Heydarian3
1Noor Research Center for Ophthalmic Epidemiology, Noor Eye Hospital.
Journal of Glaucoma
|April 26, 2023
Summary
This study determined normative optic disc indices in Iranian children, revealing associations with ocular and demographic factors. These findings are crucial for understanding pediatric eye health and potential disease indicators.
Area of Science:
- Ophthalmology
- Pediatric Optometry
- Biometry
Background:
- Optic disc indices are critical indicators of optic nerve health.
- Understanding normative values in pediatric populations is essential for early detection of eye conditions.
- Previous research has highlighted the influence of ocular and demographic factors on optic disc morphology.
Purpose of the Study:
- To establish detailed normative values for optic disc indices in a population-based sample of Iranian children.
- To investigate the association between optic disc indices and various ocular parameters, including refractive errors and biometric components.
- To explore the relationship between optic disc indices and demographic factors in the pediatric population.
Main Methods:
- A cross-sectional study was conducted in 2018 involving a large sample of Iranian children.
- Ocular biometry was performed using the Allegro Biograph device.
- Macular indices were measured using Optical Coherence Tomography (OCT) imaging.
Main Results:
- Analysis of 9051 eyes from 4784 children provided detailed normative data for vertical cup-to-disc ratio, average cup-to-disc ratio, rim area, disc area, and cup volume.
- Optic disc indices demonstrated significant associations with intraocular pressure (IOP), central corneal thickness (CCT), anterior chamber depth, lens thickness, axial length, and mean keratometry (MK).
- Demographic factors such as age, sex, and height also showed significant correlations with specific optic disc parameters, including cup volume.
Conclusions:
- The study successfully established normative values for optic disc indices in Iranian children.
- Significant associations were confirmed between optic disc indices and demographic factors, ocular biometric components, IOP, and retinal parameters.
- These findings contribute to a better understanding of optic nerve development and health in children, aiding in the identification of potential ophthalmic abnormalities.
