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Related Concept Videos

Genomics02:02

Genomics

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Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
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Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
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Next-generation sequencing technologies have created large genomic databases of a variety of animals and plants. Ever since the human genome project was completed, scientists studied the genome of primates, mammals, and other phylogenetically distant living beings. Such large-scale  studies have provided new insights into the evolutionary relationship between organisms.
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Genomic DNA in Eukaryotes00:58

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Eukaryotes have large genomes compared to prokaryotes. To fit their genomes into a cell, eukaryotic DNA is packaged extraordinarily tightly inside the nucleus. To achieve this, DNA is tightly wound around proteins called histones, which are packaged into nucleosomes that are joined by linker DNA and coil into chromatin fibers. Additional fibrous proteins further compact the chromatin, which is recognizable as chromosomes during certain phases of cell division.
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Related Experiment Video

Updated: Aug 1, 2025

Mapping Mammalian 3D Genome Interactions with Micro-C-XL
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Mapping Mammalian 3D Genome Interactions with Micro-C-XL

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Genomics expands the mammalverse.

Nathan S Upham1, Michael J Landis2

  • 1School of Life Sciences, Arizona State University, Tempe, AZ, USA.

Science (New York, N.Y.)
|April 27, 2023
PubMed
Summary

Diverse mammal genomes reveal new insights into evolutionary history. This research unlocks hidden aspects of mammalian evolution through comparative genomics.

Area of Science:

  • Genomics
  • Evolutionary Biology
  • Mammalian Biology

Background:

  • Understanding mammalian evolutionary history relies on genomic data.
  • Comparative genomics offers a powerful lens to explore evolutionary relationships.

Purpose of the Study:

  • To investigate hidden aspects of mammalian evolutionary history.
  • To leverage diverse mammal genomes for novel evolutionary insights.

Main Methods:

  • Genome sequencing of diverse mammal species.
  • Comparative genomic analysis.
  • Phylogenetic reconstruction.

Main Results:

  • Identification of novel evolutionary markers in mammal genomes.
  • Elucidation of previously unknown evolutionary relationships.

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  • Discovery of conserved and divergent genomic regions across mammals.

    • Conclusions:

    • Diverse mammal genomes provide a rich resource for evolutionary studies.
    • This work opens new avenues for understanding mammalian evolution.
    • Genomic data is crucial for uncovering evolutionary history.