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Updated: Aug 1, 2025

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Droplet Digital TRAP ddTRAP: Adaptation of the Telomere Repeat Amplification Protocol to Droplet Digital Polymerase Chain Reaction
Published on: May 3, 2019
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Detection of Telomere Transfer at Immunological Synapse
Alessio Lanna1, Clara D'Ambra2
1Sentcell UK laboratories, Rome, Italy. alessio.lanna@sentcell.life.
Methods in Molecular Biology (Clifton, N.J.)
|April 27, 2023
Abstract:
Eukaryotes solve the DNA-end replication problem synthesizing hexameric chromosome ends known as telomeres. Recent studies have uncovered unexpected functions of telomeres in linking synaptic signaling and vesicle transport, with at least one pathway directly involved in transferring telomeres through the immune synapse. These emerging forms of cellular communication may originate a new class of antiaging interventions based on telomere transplants.

