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Live Imaging and Quantification of Viral Infection in K18 hACE2 Transgenic Mice Using Reporter-Expressing Recombinant SARS-CoV-2
Published on: November 5, 2021
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Special Issue "SARS-CoV-2: Epidemiology and Pathogenesis": Editorial.
Paolo Calistri1, Harsharn Gill2, Alessio Lorusso1
1Istituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise "G. Caporale", 64100 Teramo, Italy.
Microorganisms
|April 28, 2023
Summary
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a global pandemic since 2019. This research investigates the widespread impact and characteristics of the virus.
Area of Science:
- Virology
- Epidemiology
- Public Health
Background:
- The emergence of SARS-CoV-2 in Wuhan, China, in late 2019 marked the beginning of a global health crisis.
- The virus rapidly disseminated worldwide, affecting all continents and necessitating urgent scientific and public health responses.
Discussion:
- Understanding the transmission dynamics and pathogenicity of SARS-CoV-2 is crucial for effective containment.
- The pandemic highlighted the interconnectedness of global health and the importance of international cooperation in disease surveillance.
Key Insights:
- SARS-CoV-2, the causative agent of COVID-19, demonstrated unprecedented global spread within months.
- The virus's rapid transmission underscores the need for robust pandemic preparedness strategies.
Outlook:
- Continued research into SARS-CoV-2 evolution, diagnostics, and therapeutics remains essential.
- Global surveillance and rapid response mechanisms are vital for mitigating future viral threats.
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