Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Genetic Lingo

Genetic Lingo

Genetic Screens

Genetic Screens

Genetic screens are tools used to identify genes and mutations responsible for phenotypes of interest. Genetic screens help identify individuals or a group of people at risk of developing genetic diseases and help them with early intervention, targeted therapy, and reproductive options.
Forward genetic screens
Forward or “classical” genetic screens involve creating random mutations in an organism’s DNA using radiation, mutagens, or insertion of additional bases, which...

Genetic Material

Genetic Material

Within the human body, a complex and detailed system of trillions of cells works in unison to sustain life. Each cell houses a nucleus, which contains 46 chromosomes divided into 23 pairs. Chromosomes are highly coiled structures made of the genetic material DNA. These chromosomes are essential carriers of genetic information, with half inherited from the mother through her egg and the other half from the father's sperm, combining to create the unique genetic makeup of an individual.

Human Genetics

Human Genetics

Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...

Genomics

Genomics

Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...

Gene Therapy

Gene Therapy

Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Patient Perceptions of Blockchain-Based Health Information Exchange: User-Centered Design Study.

Journal of medical Internet research·2026

Same author

Large Language Model Architectures in Health Care: Scoping Review of Research Perspectives.

Journal of medical Internet research·2025

Same author

Behavior Change Support Systems for Self-Treating Procrastination: Systematic Search in App Stores and Analysis of Motivational Design Archetypes.

Journal of medical Internet research·2025

Same author

NephroCAGE-German-Canadian Consortium on AI for Improved Kidney Transplantation Outcome: Protocol for an Algorithm Development and Validation Study.

JMIR research protocols·2023

Same author

Perceived fairness of direct-to-consumer genetic testing business models.

Electronic markets·2022

Same author

A scoping review of distributed ledger technology in genomics: thematic analysis and directions for future research.

Journal of the American Medical Informatics Association : JAMIA·2022

Search research articles

Related Experiment Video

Updated: Aug 1, 2025

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation

Published on: January 16, 2019

Direct-to-Consumer Genetic Testing on Social Media: Topic Modeling and Sentiment Analysis of YouTube Users' Comments.

Philipp A Toussaint^1,2, Maximilian Renner¹, Sebastian Lins¹

¹Department of Economics and Management Karlsruhe Institute of Technology Karlsruhe Germany.

JMIR Infodemiology

|April 28, 2023

Summary

Consumers discuss direct-to-consumer (DTC) genetic testing on YouTube, showing high interest in ancestry, health, and ethics. Users express positive attitudes towards DTC genetic testing videos and content.

Keywords:

YouTube content analysis direct-to-consumer genetic testing health information infodemiology online health information sentiment analysis social media topic modeling user discourse

More Related Videos

In Vivo Modeling of the Morbid Human Genome using Danio rerio

In Vivo Modeling of the Morbid Human Genome using Danio rerio

Published on: August 24, 2013

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry

Published on: June 21, 2018

Related Experiment Videos

Last Updated: Aug 1, 2025

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation

Determining the Likelihood of Variant Pathogenicity Using Amino Acid-level Signal-to-Noise Analysis of Genetic Variation

Published on: January 16, 2019

In Vivo Modeling of the Morbid Human Genome using Danio rerio

In Vivo Modeling of the Morbid Human Genome using Danio rerio

Published on: August 24, 2013

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry

Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry

Published on: June 21, 2018

Area of Science:

Genetics and Genomics
Social Media Analysis
Consumer Behavior

Background:

Direct-to-consumer (DTC) genetic testing provides consumers with personal genetic information.
Consumers increasingly use social media platforms like YouTube for information and discussion about DTC genetic testing.
User engagement and discourse within YouTube comments sections related to DTC genetic testing remain under-explored.

Purpose of the Study:

To investigate user discourse in YouTube comments concerning DTC genetic testing videos.
To identify prevalent topics discussed by users regarding DTC genetic testing.
To analyze user attitudes and sentiments towards DTC genetic testing as expressed in comments.

Main Methods:

Collected metadata and comments from 248 popular DTC genetic testing YouTube videos.
Applied topic modeling techniques (word frequency, bigram, structural topic modeling) to identify discussion themes.
Utilized sentiment analysis (Bing, NRC, 9-level) to gauge user attitudes and emotions.

Main Results:

Analyzed 84,082 comments, revealing six key topics: general genetic testing, ancestry, relationships, health/traits, ethics, and video reactions.
Sentiment analysis showed predominantly positive emotions, including anticipation, joy, surprise, and trust.
Overall user attitude towards DTC genetic testing videos was neutral to positive.

Conclusions:

Examining YouTube comments effectively reveals user attitudes and topics related to DTC genetic testing.
Findings indicate significant user interest in DTC genetic testing and associated social media content.
Service providers and regulators should consider evolving user interests and desires in this dynamic market.