Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Esophageal Varices-II: Clinical Features and Management01:28

Esophageal Varices-II: Clinical Features and Management

105
Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
105
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

243
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
243
Esophageal Varices-I: Introduction01:24

Esophageal Varices-I: Introduction

213
Esophageal varices are dilated, tortuous veins which are found mainly in the submucosa of the lower esophagus but which may also appear higher up or extend into the stomach. They develop due to increased pressure in the portal venous system, often as a result of liver cirrhosis. This condition scars and damages the liver, impeding normal blood flow through the portal vein. To compensate, blood seeks alternative pathways, forming fragile new vessels (varices) in the esophagus and stomach. These...
213
Peptic Ulcer Disease I: Introduction01:30

Peptic Ulcer Disease I: Introduction

228
Peptic Ulcer Disease (PUD) is characterized by mucosal excavation in the esophagus, stomach, pylorus, or duodenum. It can manifest as acute or chronic based on the extent and duration of mucosal involvement.
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
228
Disorders of Hemostasis01:24

Disorders of Hemostasis

1.0K
Hemostasis, the process that stops bleeding after a blood vessel injury, is crucial for maintaining the integrity of the circulatory system. However, disorders of hemostasis can disrupt this delicate balance, leading to either excessive clotting or bleeding. These disorders can be broadly classified into thromboembolic disorders and bleeding disorders.
Thromboembolic Disorders
Two factors primarily cause thromboembolic conditions.
1.0K
Gastritis III: Clinical Manifestations and Management01:23

Gastritis III: Clinical Manifestations and Management

347
The clinical manifestations of gastritis can vary depending on the cause and type of gastritis, but some common symptoms may include the following.
Clinical manifestations of acute gastritis
The patient with acute gastritis may have a rapid onset of symptoms, such as epigastric pain or discomfort, dyspepsia, anorexia, hiccups, or nausea and vomiting, which can last from a few hours to a few days. Erosive or hemorrhagic gastritis may cause bleeding, which may manifest as blood in vomit or as...
347

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A rare case of abdominal pain caused by Enterobius vermicularis.

BMC gastroenterology·2026
Same author

Structural and functional characterization of dihydrodiol dehydrogenase PahB recognizing high-molecular-weight PAH substrates.

Applied and environmental microbiology·2026
Same author

Virus-Like Nanoparticles for Vaccine Development and Drug Delivery.

Reviews in medical virology·2026
Same author

Structural and functional study suggests DnfC is a putative glutamine amidotransferase in the dirammox pathway.

Biochemical and biophysical research communications·2026
Same author

Electrohydraulic lithotripsy-assisted endoscopic retrograde appendicitis therapy for a giant appendiceal fecalith.

Endoscopy·2026
Same author

<i>Lactobacillus johnsonii-</i>FM1 modulates gut microbiota and secretes anticancer metabolite vanillic acid to inhibit colorectal tumorigenesis.

iMetaOmics·2026
Same journal

Very late entecavir resistance after more than 10 years of therapy in a treatment-naïve patient with chronic hepatitis B genotype D3.

Revista espanola de enfermedades digestivas·2026
Same journal

Beyond the scalpel ‒ The critical impact of lifestyle and tumor biology in non-cirrhotic hepatocellular carcinoma.

Revista espanola de enfermedades digestivas·2026
Same journal

Automated extraction of colonoscopy quality indicators from free-text reports using a prompt-based large language model pipeline.

Revista espanola de enfermedades digestivas·2026
Same journal

Ultra-processed food intake and risk of inflammatory bowel disease in the adult population ‒ A systematic review and meta-analysis.

Revista espanola de enfermedades digestivas·2026
Same journal

Persistent geographic inequalities in oesophageal cancer mortality in Spain despite overall declines.

Revista espanola de enfermedades digestivas·2026
Same journal

Diagnostic and therapeutic considerations in m.3243A>G-associated chronic intestinal pseudo-obstruction.

Revista espanola de enfermedades digestivas·2026
See all related articles

Related Experiment Video

Updated: Aug 1, 2025

Uncontrolled Hemorrhagic Shock Modeled via Liver Laceration in Mice with Real Time Hemodynamic Monitoring
06:11

Uncontrolled Hemorrhagic Shock Modeled via Liver Laceration in Mice with Real Time Hemodynamic Monitoring

Published on: May 21, 2017

8.7K

An unpredictable gastrointestinal bleed.

De-Feng Li1, Yan-Hui Tian2, Rui-Yue Shi1

  • 1Gastroenterology, Shenzhen People's Hospital, China.

Revista Espanola De Enfermedades Digestivas
|April 28, 2023
PubMed
Summary
This summary is machine-generated.

A patient with melena experienced gastrointestinal bleeding, likely due to clopidogrel use after aortic surgery. Discontinuing the medication resolved the bleeding, highlighting its potential side effect in specific cardiovascular patient populations.

Area of Science:

  • Cardiology
  • Gastroenterology
  • Pharmacology

Background:

  • Persistent melena and anemia in a 65-year-old male post-coronary artery occlusion.

More Related Videos

Endoscopic Injection Sclerotherapy Assisted by Cyanoacrylate and Clips for Gastroesophageal Varices
04:09

Endoscopic Injection Sclerotherapy Assisted by Cyanoacrylate and Clips for Gastroesophageal Varices

Published on: June 13, 2025

251
Author Spotlight: Advancing Early Detection and Treatment of Gastrointestinal Tumors
03:05

Author Spotlight: Advancing Early Detection and Treatment of Gastrointestinal Tumors

Published on: February 16, 2024

1.1K

Related Experiment Videos

Last Updated: Aug 1, 2025

Uncontrolled Hemorrhagic Shock Modeled via Liver Laceration in Mice with Real Time Hemodynamic Monitoring
06:11

Uncontrolled Hemorrhagic Shock Modeled via Liver Laceration in Mice with Real Time Hemodynamic Monitoring

Published on: May 21, 2017

8.7K
Endoscopic Injection Sclerotherapy Assisted by Cyanoacrylate and Clips for Gastroesophageal Varices
04:09

Endoscopic Injection Sclerotherapy Assisted by Cyanoacrylate and Clips for Gastroesophageal Varices

Published on: June 13, 2025

251
Author Spotlight: Advancing Early Detection and Treatment of Gastrointestinal Tumors
03:05

Author Spotlight: Advancing Early Detection and Treatment of Gastrointestinal Tumors

Published on: February 16, 2024

1.1K
  • Patient was on clopidogrel 75 mg daily following aortic sinus Valsalva aneurysm diagnosis and treatment.
  • Initial investigations including EGD, colonoscopy, and CT scans did not reveal the bleeding source.