Related Experiment Video
Updated: Aug 1, 2025
11:36
Induction of Drug-Induced, Autoimmune Hepatitis in BALB/c Mice for the Study of Its Pathogenic Mechanisms
Published on: May 29, 2020
3.0K
Autoimmune hepatitis after SARS-C¬¬oV-2 vaccination
Sandra Díez Ruiz1, Raisa Quiñones Castro2, Laura Alcoba Vega2
1Gastroenterology, Complejo Asistencial Universitario de León, España.
Revista Espanola De Enfermedades Digestivas
|April 28, 2023
Summary
SARS-CoV-2 vaccination may potentially trigger autoimmune hepatitis (AIH). This report details three cases where AIH developed following COVID-19 vaccine administration, highlighting a possible link.
Area of Science:
- Immunology
- Hepatology
- Vaccinology
Background:
- The SARS-CoV-2 vaccine has been investigated for potential links to autoimmune conditions.
- Autoimmune hepatitis (AIH) is a chronic liver disease characterized by immune system attack on liver cells.
Observation:
- Three patients developed autoimmune hepatitis (AIH) after receiving the SARS-CoV-2 vaccine.
- The onset of AIH symptoms occurred post-vaccination in these cases.
Findings:
- The presented cases suggest a potential association between SARS-CoV-2 vaccination and the development of autoimmune hepatitis.
- Further research is warranted to confirm causality and understand the underlying mechanisms.
Implications:
- These findings emphasize the importance of monitoring for autoimmune conditions post-vaccination.
- Understanding vaccine-induced autoimmunity is crucial for public health and clinical practice.
Related Concept Videos
01:29Autoimmune Disorders
563
Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
Concept and Mechanism of Autoimmune Diseases
The immune...
563
01:51Vaccinations
44.9K
Overview
44.9K
00:42Cross-reactivity
31.4K
Overview
31.4K
01:17Gastritis-II: Pathophysiology
402
Gastritis is marked by disruption of the mucosal barrier that usually protects the stomach tissue from digestive juices and manifests in acute and chronic forms.
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
In acute gastritis, the gastric mucosa becomes swollen and red and undergoes superficial erosion. Superficial ulceration may lead to bleeding.
In chronic gastritis, persistent or repeated insults lead to chronic inflammatory changes and, eventually, thinning or atrophy of the gastric tissue.
Gastritis can stem from various causes, each...
402
01:23Immunological Memory
764
Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature...
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature...
764
01:22Pericarditis I: Introduction
14
Pericarditis is defined as the inflammation of the pericardium, the thin, sac-like membrane surrounding the heart. This condition can cause significant chest pain and other symptoms, often necessitating medical intervention. The pericardium has two layers: the inner visceral layer and the outer parietal layer, separated by a small amount of fluid that reduces friction during heartbeats.Types of PericarditisPericarditis can be classified into several types based on the duration and nature of the...
14