Related Experiment Video
Updated: Aug 1, 2025

Quadruple-Checkerboard: A Modification of the Three-Dimensional Checkerboard for Studying Drug Combinations
Published on: July 24, 2021
[Countering antibiotic resistance: a new course of action is needed.]
Francesco Ferrara1, Andrea Zovi2, Eduardo Nava1
1Dipartimento Farmaceutico, Asl Napoli 3 Sud, Nola (Napoli).
Abstract:
Antibiotic resistance does not seem to be stopping despite international policies that have been aiming to combat this phenomenon for more than 10 years. The World health organization (Who) seeing the relentless growth of the issue has reiterated its recommendations that have been implemented at the national level. In fact, in Italy the new National plan against antibiotic-resistance 2022-2025 (Pncar 2022-2025) is in full operation. At Asl Napoli 3 Sud, which boasts a population of more than 1 million people, an analysis was carried out regarding antibiotic consumption in the first six months of 2022. The results showed consumption deviating from the regional and national average, thus suggesting that swift actions are needed to curb overprescription by physicians as much as possible. This work also aims to raise awareness among physicians and health care professionals of compliance with the requirements of regulatory agencies and scientific societies, so that a virtuous path toward a decisive change of pace can be taken.
More Related Videos
Related Concept Videos
Development of Antibiotic Resistance
Antibiotic Selection
Combined Effects of Drugs: Synergism
Such synergistic combinations...
Defense Against Bacterial Pathogens
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
Biological Methods for Microbial Control
Antimicrobial Effectiveness

