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Antioxidant, Antimicrobial, and Neurotoxicity (in Sh-Sy5y Cell Lines) Properties of Mg Nanoparticle System (BP@MgNPs)
Büşra Bıldır1, Duygu Nur Çobanoğlu2, Bülent Kaya3
1Department of Nutrition and Dietetics, Faculty of Health Sciences, Bingöl University, 12000, Bingöl, Türkiye.
Abstract:
Due to their distinct characteristics and possible uses in a variety of disciplines, nanoparticles have attracted a lot of attention recently. One area of interest is the synthesis of nanoparticles using natural sources such as bee pollen. The research aims to evaluate the usability of bee pollen extract-based magnesium nanoparticles (MgNPs). First, a palynological study was used to determine the plant source of bee pollen. The nanoparticle was characterized using scanning electron microscopy, energy dispersive X-ray analysis, transmission electron microscopy, X-ray diffractometry, and Fourier transform infrared spectroscopy. The results revealed cubic-shaped MgNPs with an average size range of 36-40 nm. Afterward, nanoparticles were evaluated for their antioxidant, antimicrobial, and neurotoxic properties. It was determined that the total antioxidant capacity, phenolic (TPC), flavonoid (TFC) content, DPPH radical scavenging, and antimicrobial activity of the nanoparticles were lower than pollen extract. At the same time, nanoparticles have less toxicity than bee pollen.
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