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Time to Introduce Nerve Density in Cancer Histopathologic Assessment
Hubert Hondermarck1,2, Chen Chen Jiang1,2
1School of Biomedical Sciences and Pharmacy, College of Health, Medicine and Wellbeing, University of Newcastle, Callaghan, New South Wales, Australia.
Abstract:
The density of nerves in the tumor microenvironment is increasingly reported to be associated with worse clinical outcome in various cancers. Therefore, it is time to consider the assessment of nerve density in clinical cancer pathology, and interestingly, the development of artificial intelligence may facilitate this clinical translation. See related article by Perez-Pacheco et al., p. 2501.
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