Related Experiment Video

Updated: Aug 1, 2025

Using In Vitro Fluorescence Resonance Energy Transfer to Study the Dynamics Of Protein Complexes at a Millisecond Time Scale
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Using In Vitro Fluorescence Resonance Energy Transfer to Study the Dynamics Of Protein Complexes at a Millisecond Time Scale

Published on: March 14, 2019

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CAND1 orchestrates CRLs through rock and roll.

Yuan Xie1, Minglei Zhao1

  • 1Department of Biochemistry and Molecular Biology, University of Chicago, Chicago, IL, USA.

Cell
|April 28, 2023
PubMed
Summary

Proper protein degradation is vital for cell function. Baek et al. discovered that CAND1 regulates the assembly and disassembly of Cullin-RING ligases (CRL), crucial for protein turnover.

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