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Systematic review of economic evaluations for paediatric pulmonary diseases

Mutsawashe Chitando1, Susan Cleary2, Lucy Cunnama2

  • 1Health Economics Unit and Division, School of Public Health and Family Medicine, Faculty of Health Sciences, University of Cape Town, Anzio Road, Observatory, Cape Town, 7925, South Africa. mutsawashechitando@yahoo.com.

Cost Effectiveness and Resource Allocation : C/E
|April 30, 2023
PubMed

Insights

Economic evaluations guide decisions on managing childhood lung diseases. More studies in low- and middle-income countries (LMICs) are needed to improve evidence-based healthcare for these common pediatric conditions.

Area of Science:

  • Pediatric Pulmonology
  • Health Economics
  • Global Health

Background:

  • Pediatric pulmonary diseases are a major cause of mortality in children under five worldwide.
  • Economic evaluations (EEs) are crucial for guiding healthcare decisions to reduce the burden of these diseases.
  • This systematic review focuses on EEs for inpatient management of pediatric pulmonary diseases globally.

Purpose of the Study:

  • To systematically review economic evaluations on the inpatient management of pediatric pulmonary diseases.
  • To identify trends and gaps in the existing literature.
  • To inform decision-making for resource allocation in pediatric respiratory healthcare.

Main Methods:

  • Systematic review of EEs published between 2010 and 2022.
  • Searches conducted across major databases including PubMed, Web of Science, MEDLINE, PEDE, and Cochrane Library.
  • Data extraction guided by CHEERS checklist and analysis using Microsoft Excel and R software.

Main Results:

  • Twenty-two articles met inclusion criteria, encompassing cost-effectiveness, cost-utility, cost-minimization, and cost analyses.
  • Twelve studies originated from high-income countries (HICs) and ten from low- and middle-income countries (LMICs).
  • Key conditions studied included asthma (8 articles) and pneumonia (11 articles).

Conclusions:

  • The current body of economic evaluations for pediatric pulmonary diseases is limited, particularly in LMICs.
  • There is a need for more EEs in LMICs to support evidence-based decision-making.
  • Increased EEs can enhance healthcare outcomes for children with pulmonary diseases globally.
Abstract

Keywords:
Economic evaluationPaediatricPulmonary diseaseSystematic review

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