Related Experiment Video
Updated: Aug 1, 2025

Acupoint Application Combined with Acupressure as an Adjunctive Therapy for Chemotherapy-Induced Nausea and Vomiting
Published on: June 21, 2024
Acupressure Versus Ondansetron Usage for Postoperative Nausea and Vomiting After Gynecologic Surgeries
Elif Ongel1, Ezgi Erdag1, Esra Adiyeke1
1Anesthesiology and Reanimation, Sancaktepe Martyr Prof. Dr. Ilhan Varank Education and Research Hospital, Istanbul, TUR.
Acupressure at the PC6 point showed similar effectiveness to intravenous ondansetron in reducing postoperative nausea and vomiting (PONV) after gynecological surgery. However, neither intervention fully prevented early PONV, with 50% of patients experiencing moderate to high nausea.
Area of Science:
- Anesthesiology
- Integrative Medicine
- Surgical Nursing
Background:
- Postoperative nausea and vomiting (PONV) is a common complication following gynecological surgery.
- Pharmacologic and non-pharmacologic interventions are used to manage PONV.
- Acupressure, a non-invasive technique, involves applying pressure to specific acupoints, such as the PC6 point.
Purpose of the Study:
- To compare the efficacy of PC6 acupressure with intravenous ondansetron in managing PONV after gynecological surgeries.
- To identify factors associated with early postoperative nausea scores.
Main Methods:
- A prospective, randomized, single-centered study involving 102 patients undergoing gynecological surgery under general anesthesia.
- Patients were randomized to receive either intravenous ondansetron (Group O) or PC6 acupressure bands (Group B).
- PONV and pain scores were assessed at multiple time points post-surgery; patients were also grouped by early nausea severity for factor analysis.
Main Results:
- No significant difference in overall postoperative pain, nausea, or vomiting scores was observed between the acupressure and ondansetron groups.
- Fifty percent of patients experienced moderate to high early postoperative nausea, with 10% requiring additional anti-emetic medication.
- Factors significantly associated with early PONV included motion sickness history, operation time, and early postoperative pain scores.
Conclusions:
- PC6 acupressure is a viable alternative to intravenous ondansetron for PONV management after gynecological procedures, offering similar efficacy.
- Neither intervention alone was sufficient to adequately control early PONV in 50% of patients.
- Identifying associated factors like operation time and pain is crucial for optimizing PONV prevention strategies.
Related Concept Videos
Chemotherapy-Induced Nausea and Vomiting: 5-HT3 Receptor Antagonists
Chemotherapy-Induced Nausea and Vomiting: Neurokinin-1 Receptor Antagonists
Chemotherapy-Induced Nausea and Vomiting: Dopamine Receptor Antagonists
Phenothiazines, such as prochlorperazine...
Chemotherapy-Induced Nausea and Vomiting: Cannabinoids
Two synthetic agonists of THC,...
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Drugs Affecting GI Tract Motility: Opioids as Antidiarrheal Agents
Opioids, widely used antidiarrheal agents, mitigate diarrhea by slowing down...

