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Updated: Aug 1, 2025

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Laparoscopic appendectomy vs open appendectomy during pregnancy: a systematic re-view.

A Rountis1,2, D Dimitroulis2,3, N Nikiteas2,3

  • 11st Department of Obstetrics and Gynecology, "Alexandra" General Hospital, Athens, Greece.

Hippokratia
|May 1, 2023
PubMed
Summary

Laparoscopic appendectomy during pregnancy is safer than open surgery. This approach reduces risks of fetal demise and preterm delivery for expectant mothers undergoing appendicitis treatment.

Keywords:
Open appendectomyacute appendicitislaparoscopic appendectomylaparoscopic appendectomy vs open appendectomypregnancy appendectomypregnancy appendicitis surgery

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Area of Science:

  • Obstetrics and Gynecology
  • Surgical Gastroenterology
  • Maternal-Fetal Medicine

Background:

  • Acute appendicitis and cholecystitis are common non-obstetrical surgical emergencies in pregnancy.
  • Surgical intervention is recommended but must balance maternal health with fetal safety.
  • Early diagnosis and prompt intervention are crucial for favorable outcomes in pregnant patients.

Purpose of the Study:

  • To systematically review and compare laparoscopic versus open surgery for acute appendicitis in pregnant patients.
  • To determine if laparoscopic appendectomy offers improved safety outcomes compared to open surgery during pregnancy.

Main Methods:

  • Systematic review of major medical databases.
  • Inclusion of published studies comparing laparoscopic and open appendectomy in pregnancy.
  • Statistical analysis of extracted data from relevant studies.

Main Results:

  • Fifteen studies involving 2,837 pregnant patients were analyzed.
  • Laparoscopic surgery (1,103 patients) showed a fetal demise rate of 2.44% and preterm delivery rate of 9.79%.
  • Open surgery (1,656 patients) had a fetal demise rate of 2.64% and preterm delivery rate of 10.7%.

Conclusions:

  • Laparoscopic appendectomy appears to be a safer treatment option for acute appendicitis during pregnancy.
  • The data suggest a reduced risk of fetal demise and preterm delivery with the laparoscopic approach.
  • Optimizing surgical techniques is essential for favorable maternal and fetal outcomes.