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Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis
Published on: September 26, 2018
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Cardiovascular Risk Management in Persons with Dementia
Charlotte Nijskens1, Marieke Henstra1, Hanneke Rhodius-Meester1,2,3
1Department of Internal Medicine, Amsterdam UMC location Vrije Universiteit Amsterdam, Geriatrics section, Amsterdam, The Netherlands.
Journal of Alzheimer'S Disease : JAD
|May 1, 2023
Summary
Cardiovascular risk management in dementia patients requires careful consideration of life expectancy and potential harms. Guidelines need adaptation to prevent adverse events and overtreatment in this population.
Area of Science:
- Gerontology
- Neurology
- Cardiology
Background:
- Global increase in dementia prevalence, including Alzheimer's disease.
- Individuals with dementia have elevated risk for atherosclerotic cardiovascular disease.
- Current cardiovascular risk management guidelines exclude individuals with dementia.
Purpose of the Study:
- To review and adapt current cardiovascular risk management guidelines for individuals with dementia.
- To discuss considerations for treating hypertension and hyperlipidemia in dementia patients.
- To prevent major adverse cardiovascular events (MACE) in this population.
Main Methods:
- Narrative review of existing cardiovascular risk management guidelines.
- Discussion of guideline applicability to individuals with dementia.
- Analysis of factors influencing treatment decisions and monitoring.
Main Results:
- Survival is shorter in persons with dementia, necessitating evaluation of life expectancy and treatment wishes.
- Risk assessment tools may overestimate MACE risk and CVRM benefits in dementia.
- Close monitoring is crucial due to high risk of adverse drug events and overtreatment.
Conclusions:
- CVRM in dementia requires individualized approaches, prioritizing patient longevity and preferences.
- Risk assessment tools should be used cautiously in this population.
- Deprescribing should be considered for individuals with dementia and limited life expectancy.
Keywords:
Alzheimer’s diseasecardiovascular diseasescardiovascular riskcontroldementiahypercholesterolemiahypertensionpreventionMore Related Videos
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