Part 1: The Clinical Applications of Left Ventricular Myocardial Strain

Area of Science:

• Cardiology
• Cardio-oncology
• Medical imaging

Background:

• Cardiovascular disease and heart failure prevalence is rising.
• Left ventricular ejection fraction may not accurately reflect systolic function in all cardiac conditions.
• Reduced ejection fraction can indicate advanced, irreversible disease stages.

Purpose of the Study:

• To review myocardial strain concepts.
• To discuss emerging clinical applications of global longitudinal strain.
• To highlight strain's role in cardio-oncology.

Main Methods:

• Literature review of myocardial strain.
• Analysis of global longitudinal strain applications.
• Focus on early detection of cardiac dysfunction.

Main Results:

• Myocardial strain is a robust tool for early heart disease identification.
• Strain detects subtle left ventricular systolic dysfunction.
• Global longitudinal strain shows promise in cardio-oncology.

Conclusions:

• Myocardial strain is a valuable metric for assessing left ventricular systolic function.
• Strain imaging aids in early diagnosis and risk stratification.
• Further research into strain's clinical utility in cardio-oncology is warranted.