Related Experiment Video
Updated: Jul 31, 2025
Enhancing the Development and Growth of Infant Cerebral Palsy Rats Using Selective Spinal Manipulations
Published on: February 2, 2024
Predictors of Risk for Cerebral Palsy: A Review
Tanochni Mohanty1, Sibi Daniel Joseph, Pradeep Kumar Gunasekaran
1Department of Pediatric Physiotherapy (Ms Mohanty), JSS College of Physiotherapy, Mysuru, Karnataka, India; Department of Musculoskeletal Physiotherapy (Dr Joseph), Lokmanya Tilak College of Physiotherapy, Navi Mumbai, Maharashtra, India; Department of Pediatrics (Drs Gunasekaran and Saini), All India Institute of Medical Sciences, Jodhpur, Rajasthan, India; Department of Pediatrics (Dr Doreswamy), JSS Medical College and Hospital, Mysuru, Karnataka, India.
Purpose:
To identify the earliest predictors of risk for diagnosis of cerebral palsy (CP).
Methods:
A comprehensive literature search was conducted using various databases. The publications were reviewed to identify risk factors for CP from conception to early infancy. Studies were critically appraised with Joanna Briggs Institute guidelines for quality appraisal and evaluated for risk of bias using the Agency for Health Care Research and Quality guidelines.
Results:
The initial search yielded 129 studies and 20 studies were included. Forty-seven risk factors for CP were extracted of which several were duplicate terms. The significant risk factors found to be indicative of CP were low birth weight (<1500 g), birth at less than 28 weeks of gestational age, periventricular leukomalacia, grade 3 or 4 intraventricular hemorrhage, preeclampsia, prematurity, an Apgar score of less than 4 at the first minute, birth asphyxia, preterm premature rupture of membrane, and absent fidgety movements.
Conclusion:
Twenty-three factors were consistently reported as predictors of CP.
