Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Signs of Puberty01:27

Signs of Puberty

480
Puberty is a critical phase, typically beginning between the ages of 8 and 13 in girls and 9 and 14 in boys, though timing can vary based on genetics, environmental factors, and overall health. This period is characterized by the development of secondary sexual characteristics and the attainment of reproductive potential. Endocrine changes underpin puberty, with hormonal surges of Luteinizing Hormone (LH) and Follicle-Stimulating Hormone (FSH) instigated by Gonadotropin-Releasing Hormone (GnRH)...
480
Psychosexual Stages of Personality: Latency01:16

Psychosexual Stages of Personality: Latency

540
Following the phallic stage in Freud's theory of psychosexual development, children enter a phase called the latency period, which lasts from approximately six to twelve years of age. Unlike earlier stages, where sexual impulses played a central role, Freud believed these impulses are repressed during the latency period, becoming part of the unconscious. This stage is often described as a time of psychological calm after the turbulence of the phallic stage.
The latency period is not...
540
Nature and Nurture01:10

Nature and Nurture

20.6K
Many human characteristics, like height, are shaped by both nature—in other words, by our genes—and by nurture, or our environment. For example, chronic stress during childhood inhibits the production of growth hormones and consequently reduces bone growth and height. Scientists estimate that 70-90% of variation in height is due to genetic differences among individuals, and 10-30% of variation in height is due to differences in the environments that individuals experience,...
20.6K
Conduct Disorder01:28

Conduct Disorder

95
Conduct disorder is a complex mental health diagnosis characterized by a repetitive and persistent pattern of behavior that violates societal norms, the rights of others, or age-appropriate rules. The diagnostic criteria for conduct disorder require the presence of at least three problematic behaviors within the past 12 months, with at least one occurring in the past six months. These behaviors are grouped into four categories: aggression toward people and animals; destruction of property;...
95
Menopause01:28

Menopause

213
Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...
213
Socioemotional Experience and Gender Development01:30

Socioemotional Experience and Gender Development

58
Social-emotional experiences and cultural influences play significant roles in shaping gender development. During middle childhood, from ages 6 to 11, peer groups become dominant in reinforcing gender norms. Children in this age group often align with same-gender peer groups, which actively encourage behaviors that conform to traditional gender roles. For instance, boys may be discouraged from engaging in activities perceived as feminine, reinforcing culturally dictated norms about masculinity...
58

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pediatric Endocrinology in Office Practice - The Way Forward.

Indian journal of pediatrics·2023
Same author

Prevalence and Determinants of Occurrence of Dyslipidemia in Subjects with Type 1 Diabetes Mellitus.

Indian journal of pediatrics·2022
Same author

Utility of the New Indian Society of Paediatric and Adolescent Endocrinology (ISPAE) Guidelines for Congenital Hypothyroidism Screening in a High Risk Unit.

Indian journal of pediatrics·2020
Same author

A Study on New IAP 2015 Growth References in Rural South Indian Children.

Indian journal of pediatrics·2020

Related Experiment Video

Updated: Jul 31, 2025

Determination of Reproductive Competence by Confirming Pubertal Onset and Performing a Fertility Assay in Mice and Rats
06:38

Determination of Reproductive Competence by Confirming Pubertal Onset and Performing a Fertility Assay in Mice and Rats

Published on: October 13, 2018

15.5K

Delayed Puberty.

Swathi Mohanraj1, Hemchand Krishna Prasad2

  • 1Department of Pediatrics, Mehta Multispeciality Hospitals India Pvt. Ltd., Chennai, Tamil Nadu, India.

Indian Journal of Pediatrics
|May 1, 2023
PubMed
Summary
This summary is machine-generated.

Delayed puberty, a common endocrine concern, is diagnosed when pubertal signs are absent by specific ages. Early assessment and appropriate hormone replacement therapy are crucial for achieving adult sexual maturity.

Keywords:
Delayed pubertyGonadotrophinMenarcheTanner’s staging

More Related Videos

A Hyperandrogenic Mouse Model to Study Polycystic Ovary Syndrome
08:20

A Hyperandrogenic Mouse Model to Study Polycystic Ovary Syndrome

Published on: October 2, 2018

11.3K
Rodent Estrous Cycle Monitoring Utilizing Vaginal Lavage: No Such Thing As a Normal Cycle
09:05

Rodent Estrous Cycle Monitoring Utilizing Vaginal Lavage: No Such Thing As a Normal Cycle

Published on: August 30, 2021

7.5K

Related Experiment Videos

Last Updated: Jul 31, 2025

Determination of Reproductive Competence by Confirming Pubertal Onset and Performing a Fertility Assay in Mice and Rats
06:38

Determination of Reproductive Competence by Confirming Pubertal Onset and Performing a Fertility Assay in Mice and Rats

Published on: October 13, 2018

15.5K
A Hyperandrogenic Mouse Model to Study Polycystic Ovary Syndrome
08:20

A Hyperandrogenic Mouse Model to Study Polycystic Ovary Syndrome

Published on: October 2, 2018

11.3K
Rodent Estrous Cycle Monitoring Utilizing Vaginal Lavage: No Such Thing As a Normal Cycle
09:05

Rodent Estrous Cycle Monitoring Utilizing Vaginal Lavage: No Such Thing As a Normal Cycle

Published on: August 30, 2021

7.5K

Area of Science:

  • Pediatric Endocrinology
  • Reproductive Medicine
  • Adolescent Health

Background:

  • Delayed puberty is defined by the absence of secondary sexual characteristics by established age thresholds.
  • It can stem from hypogonadotropic hypogonadism, hypergonadotropic hypogonadism, or eugonadotropic eugonadism.
  • Constitutional Delay of Growth and Puberty (CDGP) and systemic illnesses are key differential diagnoses.

Purpose of the Study:

  • To outline the diagnostic criteria and evaluation process for delayed puberty.
  • To discuss the differential diagnoses and underlying etiologies of delayed puberty.
  • To describe the principles and methods of pubertal induction and hormone replacement therapy.

Main Methods:

  • Clinical assessment including Tanner staging and anthropometry.
  • Hormonal assays (gonadotropins) and bone age measurement.
  • Imaging (ultrasound) and genetic testing (karyotyping) as indicated.
  • Gonadotropin-releasing hormone (GnRH) analogue stimulation test to differentiate causes.

Main Results:

  • Delayed puberty evaluation involves a stepwise approach combining clinical, hormonal, and imaging data.
  • Karyotyping is essential in specific patient groups (e.g., girls with short stature, boys with hypergonadotropic hypogonadism).
  • GnRH analogue testing aids in distinguishing CDGP from hypogonadotropic hypogonadism.

Conclusions:

  • Accurate diagnosis of delayed puberty requires comprehensive evaluation to identify the underlying cause.
  • Hormone replacement therapy should be initiated judiciously to mimic physiological pubertal progression.
  • Successful pubertal induction is critical for achieving adult sexual maturity and overall health.