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Updated: Jul 31, 2025

Author Spotlight: Advancing Research on Candida albicans Biofilm-Associated Prosthetic Joint Infections
Published on: February 2, 2024
The Impact of a Dedicated Multidisciplinary Team Approach for Prosthetic Joint Infections of the Lower Limb
James D Sires1,2, Kim Pham1, Christopher J Wilson1,2
1College of Medicine and Public Health, Flinders University, Adelaide, Australia.
Introduction:
Prosthetic joint infections (PJI) of the hip and knee have significant morbidity and mortality, and present with varying local, host and microbiological factors. Given the broad presentation and complexity of PJI's, we developed a dedicated multidisciplinary team (MDT) to manage this complex patient cohort, and report on our early outcomes.
Methods:
This was a retrospective observational study of all patients diagnosed with a prosthetic joint infection of the hip or knee (n = 71) at our institution during a 4.5-year period. Patients treated after development of the MDT (post-MDT) (n = 44), were compared to a control group prior establishment of the MDT (pre-MDT) (n = 27).
Results:
85.2% of individuals in the pre-MDT, and 85.7% of individuals in the post-MDT group were considered cured at a minimum 2 years post-operatively according to the Delphi-based definition. The total number of admissions to hospital (2.44 vs. 1.84) and total number of antibiotics used (3.37 vs. 2.75) decreased in the post-MDT group; however, differences were not considered statistically significant.
Discussion:
Implementation of a dedicated MDT in the management of individuals with PJI's of the lower limb at our hospital has allowed early and effective collaboration between healthcare personnel, with early promising results. Given the broad nature of PJI, future studies are ongoing to determine modifiable risk factors to reduce the incidence and improve outcomes of individuals with PJI's where systems can then be implemented into already established MDTs to achieve the best clinical outcome for our patients.
Supplementary Information:
The online version contains supplementary material available at 10.1007/s43465-023-00842-5.
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