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Updated: Jul 31, 2025
07:15
Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
Published on: January 21, 2020
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Obesity as a risk factor for periodontitis - does it really matter?
1Dental Core Trainee, East Lancashire NHS Hospitals Trust, Blackburn, UK. mohammed.z.adam@outlook.com.
Evidence-Based Dentistry
|May 2, 2023
Summary
Obesity is linked to an increased risk of periodontitis in adults. While human studies show a positive association, a direct causal link between obesity and this gum disease remains unproven.
Area of Science:
- Oral Health and Systemic Diseases
- Epidemiology
- Public Health
Background:
- Obesity is a growing global health concern.
- Periodontitis is a common inflammatory gum disease.
- The relationship between obesity and periodontitis requires further investigation.
Purpose of the Study:
- To systematically review existing literature on the association between obesity and periodontitis.
- To synthesize findings from human and animal studies.
Main Methods:
- Systematic search of major databases (MEDLINE, Scopus, Web of Science, Cochrane Library) for studies published between January 2000 and June 2022.
- Inclusion of case-control, cross-sectional, and cohort studies in adults aged 18-70 years.
- Qualitative analysis of 15 selected studies, assessing risk of bias using the Newcastle-Ottawa Quality Assessment Scale.
Main Results:
- Fifteen studies, involving 1982 initially identified, met the inclusion criteria.
- Human studies predominantly indicated a positive association between obesity and periodontitis.
- Animal studies presented conflicting results regarding this association.
Conclusions:
- A positive association exists between obesity and periodontitis in humans.
- Current evidence does not establish a causal relationship between obesity and periodontitis.
- Further research is needed to elucidate the complex relationship and potential causality.
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