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Published on: June 13, 2019
The Verriest Lecture: Pathways to color in the eye and brain
Abstract:
In common with the majority of New World monkeys, marmosets show polymorphic color vision by allelic variation of X-chromosome genes encoding opsin pigments in the medium/long wavelength range. Male marmosets are thus obligate dichromats ("red-green color blind"), whereas females carrying distinct alleles on X chromosomes show one of three trichromatic phenotypes. Marmosets thus represent a "natural knock-out" system enabling comparison of red-green color vision in dichromatic and trichromatic visual systems. Further, study of short-wave (blue) cone pathways in marmosets has provided insights into primitive visual pathways for depth perception and attention. These investigations represent a parallel line to clinical research on color vision defects that was pioneered in studies by Guy Verreist, whom we honor in this eponymous lecture.
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