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Case report: Congenital mesoblastic nephroma
Kristen De Wilde1, Jamshed Zuberi2
1St. George's School of Medicine, 3500 Sunrise Hwy, Great River, NY 11739, United States of America.
International Journal of Surgery Case Reports
|May 4, 2023
Summary
Congenital mesoblastic nephroma, a common infant kidney tumor, was diagnosed in a one-day-old neonate. Surgical resection was successful, with close monitoring recommended for potential recurrence or paraneoplastic syndromes.
Area of Science:
- Pediatric Oncology
- Nephrology
- Surgical Pathology
Background:
- Congenital mesoblastic nephroma (CMN) is the most common renal tumor in infants.
- Early identification and accurate pathology are critical for prognosis and treatment planning.
Observation:
- A one-day-old neonate presented with a left upper quadrant mass.
- Ultrasound revealed a heterogeneous solid mass infiltrating the left kidney hilum.
- The patient underwent a successful left radical nephrectomy.
Findings:
- Pathology confirmed classic congenital mesoblastic nephroma, stage I, with complete tumor resection.
- The infant experienced transient hypertensive episodes.
- Monitoring of calcium and renin levels is advised.
Implications:
- While typically benign, CMN requires vigilant follow-up for recurrence and potential paraneoplastic syndromes.
- Certain CMN subtypes carry a risk of malignant transformation.
- Long-term surveillance is essential in the initial years of life.

