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Metastasis

Metastasis

Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...

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Related Experiment Video

Updated: Jul 31, 2025

Advanced Animal Model of Colorectal Metastasis in Liver: Imaging Techniques and Properties of Metastatic Clones

Advanced Animal Model of Colorectal Metastasis in Liver: Imaging Techniques and Properties of Metastatic Clones

Published on: November 30, 2016

Breast Cancer Metastasis to Colon.

Fatima Z Arif¹, Rebecca O Breese¹, Rachel Burke¹

¹Department of Surgery, Eastern Virginia Medical School, Norfolk, VA, USA.

The American Surgeon

|May 5, 2023

Summary

This case report details an extremely rare instance of breast cancer metastasizing to the colon. The patient presented with gastrointestinal bleeding, highlighting the importance of considering metastatic disease in the differential diagnosis.

Area of Science:

Oncology
Gastroenterology
Pathology

Background:

Breast cancer metastasis to the colon is a rare clinical event.
Fewer than 20 cases have been documented in medical literature.

Keywords:

breast, colorectal colon cancer invasive ductal breast carcinoma metastasis

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Metastatic disease can present with diverse gastrointestinal symptoms.