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Nonlinear effects and effect modification at the participant-level in IPD meta-analysis part 2: methodological

Nadine Marlin1, Peter J Godolphin2, Richard L Hooper1

  • 1Methodology Research Unit, Centre for Evaluation and Methods, Wolfson Institute of Population Health, Queen Mary University of London, 58 Turner Street, London E1 2AB, UK.

Journal of Clinical Epidemiology
|May 5, 2023
PubMed
Abstract

Keywords:
Effect modificationFractional polynomialsIndividual participant data meta-analysisInteractionMethodologyNonlinearOne- and two-stage modelsRestricted cubic splinesSample size

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