Related Experiment Video
Updated: Aug 5, 2026

Profiling Maternal Behavior Responses During Whole-Brain Imaging
Published on: January 24, 2025
Introduction to Trial-Level Subgroup Analysis: A Tutorial
Peter J Godolphin1, Conor D Tweed1, David J Fisher1
1UCL Innovative Clinical Trials Unit, Institute of Clinical Trials and Methodology University College London London UK.
Abstract:
This tutorial introduces the concept of trial-level subgroup analysis in meta-analysis. We describe the rationale for conducting subgroup analyses, distinguish trial-level from participant-level characteristics, outline how to properly interpret effects within subgroups, and illustrate how to perform a trial-level subgroup analysis, including formal statistical testing for differences between subgroups. A complementary micro-learning module is provided to support additional learning of these concepts.
More Related Videos
Related Concept Videos
Comparing the Survival Analysis of Two or More Groups
Introduction To Survival Analysis
The primary goal of survival analysis is to estimate survival time—the time until a...
Testing a Claim about Population Proportion
There are two methods of testing a claim about a population proportion: (1) Using the sample proportion from the data where a binomial distribution is approximated to the normal distribution and (2) Using the binomial probabilities calculated from the data.
The first method uses normal distribution as an approximation to the binomial distribution. The requirements are as follows: sample size is large...
Sampling Plans
Random sampling is a method where each member of the population has an equal chance of being selected for the sample. It involves selecting individuals randomly, often using random number generators or lottery-type methods. For example, when analyzing the properties of a...
Introduction to Test of Independence
The test statistic for a test of independence is similar to that of a goodness-of-fit test:
Statistical Analysis: Overview
One of the most commonly used statistical quantifiers is the mean, which is the ratio between the sum of the numerical values of all results and the...

