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Local coordination between intracortical bone remodeling and vascular development in human juvenile bone

Christina Møller Andreasen1, Bilal Mohamad El-Masri1, Birgit MacDonald2

  • 1Molecular Bone Histology lab, Pathology Research Unit, Department of Clinical Research, University of Southern Denmark, Denmark; Department of Pathology, Odense University Hospital, Odense, Denmark; Department of Molecular Medicine, University of Southern Denmark, Denmark.

Bone
|May 7, 2023
PubMed
Summary

Intracortical bone resorption is coordinated with vascular development. Osteoclasts drive this process by expressing vascular endothelial growth factor-A (VEGFA), guiding the vascular network

Keywords:
Blood vesselsBone remodelingCortical boneCouplingVEGFA-signaling

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