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Updated: Jul 31, 2025

A Simple Composite Phenotype Scoring System for Evaluating Mouse Models of Cerebellar Ataxia
Published on: May 21, 2010
Hypomagnesemia, a Rare Cause of Reversible Ataxia
Daniel López Domínguez1, Juan Rodríguez Álvarez-Cienfuegos2, Carla Herminia Vera Cáceres3
1Movement Disorders Unit, Ataxia Unit, Neurology Department. Josep Tueta Hospital, Girona, Spain.
Background:
A 61-year-old male patient presented with cerebellar syndrome, which had progressively worsened for 10 days, followed by a tonic-clonic seizure.
Phenomenology Shown:
Blood analysis showed severe hypomagnesemia and a brain MRI showed T2 hyperintensity in the cerebellar hemispheres (Figure 1). Therefore, the final diagnosis was cerebellar syndrome and epileptic seizures secondary to severe hypomagnesemia.
Educational Value:
In cases of subacute onset of ataxia, the possibility of ataxia secondary to hypomagnesemia should be considered, as it can be diagnosed with a basic blood test and there are potentially life-threatening outcomes in the absence of treatment, with a reversible course following early supplementation.
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