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CATAMENIAL DIABETIC KETOACIDOSIS.

Z Hekimsoy1, E B Eniseler2, N Erdem2

  • 1Division of Endocrinology, Celal Bayar University - Faculty of Medicine, Manisa, Turkey.

Acta Endocrinologica (Bucharest, Romania : 2005)
|May 8, 2023
PubMed
Summary
This summary is machine-generated.

Catamenial diabetic ketoacidosis (DKA) is linked to menstrual cycles. Adjusting insulin before periods may prevent DKA in women with type 1 diabetes mellitus.

Keywords:
catamenialdiabetic ketoacidosismenstruation

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Area of Science:

  • Endocrinology
  • Reproductive Health
  • Metabolic Disorders

Background:

  • Diabetic ketoacidosis (DKA) is a serious complication of diabetes.
  • Hormonal fluctuations during the menstrual cycle can impact glycemic control.
  • Catamenial DKA, a rare form of DKA, is associated with menstruation.

Purpose of the Study:

  • To investigate the link between the menstrual cycle and diabetic ketoacidosis.
  • To highlight the importance of considering catamenial DKA in susceptible patients.
  • To propose a management strategy for preventing menstrual cycle-associated DKA.

Main Methods:

  • Case report of a 21-year-old female with type 1 diabetes mellitus.
  • Analysis of recurrent DKA episodes occurring prior to menstrual bleeding.
  • Review of potential contributing factors for DKA development.

Main Results:

  • The patient experienced recurrent DKA episodes exclusively a few days before her menstrual period.
  • No other common precipitating factors for DKA were identified.
  • This pattern suggests a strong association between menstruation and DKA in this individual.

Conclusions:

  • Catamenial DKA should be considered in women with diabetes presenting with recurrent DKA without other clear causes.
  • Proactive insulin dose adjustment prior to menstruation may prevent hyperglycemia and DKA.
  • Personalized management strategies are crucial for patients with type 1 diabetes and menstrual cycle-related glycemic variability.