Multiresistant Staphylococcus epidermidis as a pathogen

Annals of Clinical Research
|January 1, 1986
PubMed

Insights

Multiresistant Staphylococcus epidermidis (MSE) strains are common in hospitals, causing significant infections like wound and urinary tract infections. Over half of all Staphylococcus epidermidis strains isolated were multiresistant.

Area of Science:

  • Microbiology
  • Clinical Medicine
  • Infectious Diseases

Background:

  • Staphylococcus epidermidis is a common cause of hospital-acquired infections.
  • The increasing prevalence of antimicrobial resistance poses a significant threat to patient care.

Purpose of the Study:

  • To investigate the occurrence and clinical significance of multiresistant Staphylococcus epidermidis (MSE) strains.
  • To determine the role of MSE as a pathogen in various hospital departments.

Main Methods:

  • Prospective study of 178 in-patients from whom MSE was isolated over six months.
  • Definition of multiresistant strains as those resistant to ≥3 antimicrobial agents.
  • Daily monitoring of patients for signs of infection and identification of the causative pathogen.

Main Results:

  • Multiresistant Staphylococcus epidermidis accounted for 57.9% of all isolated Staphylococcus epidermidis strains.
  • Clinical infection occurred in 155 patients; MSE was the likely pathogen in 115 (65%).
  • Common infections included wound infections (43%) and urinary tract infections (37%).

Conclusions:

  • Multiresistant Staphylococcus epidermidis is a prevalent pathogen in university hospital settings.
  • MSE is frequently implicated in significant nosocomial infections, particularly wound and urinary tract infections.
  • Effective antimicrobial stewardship is crucial to manage infections caused by MSE.

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