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Updated: Jul 30, 2025

High-Resolution Cardiac Positron Emission Tomography/Computed Tomography for Small Animals
Published on: December 16, 2022
Imaging Acute Myocarditis with 68Ga-DOTANOC PET/CT.
Jasim Jaleel1, Chetan D Patel1, Khangembam Bangkim Chandra1
1Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
Somatostatin receptor (SSTR) imaging aids in diagnosing acute myocarditis. In a case study, 68Ga-DOTANOC PET/CT revealed myocardial uptake, indicating SSTR imaging
Area of Science:
- Nuclear medicine
- Cardiology
- Radiology
Background:
- Acute myocarditis diagnosis can be challenging.
- Somatostatin receptor (SSTR) imaging shows promise in evaluating cardiac inflammation.
Purpose of the Study:
- To illustrate the utility of SSTR imaging in a patient with clinically diagnosed acute myocarditis.
- To highlight SSTR imaging as a potential biomarker for active myocardial inflammation.
Main Methods:
- Case presentation of a 54-year-old male with acute myocarditis.
- Utilized 68Ga-DOTANOC positron emission tomography/computed tomography (PET/CT) for imaging.
Main Results:
- PET/CT demonstrated diffuse left ventricular myocardial uptake of 68Ga-DOTANOC.
- This uptake suggests active inflammation in the myocardium.
Conclusions:
- SSTR imaging can serve as a surrogate marker for active inflammation in acute myocarditis.
- SSTR imaging may guide biopsy site selection, assess treatment response, and aid in prognostication.
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