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Updated: Jul 30, 2025
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Nasal Brushing Sampling and Processing Using Digital High Speed Ciliary Videomicroscopy – Adaptation for the COVID-19 Pandemic
Published on: November 7, 2020
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[COVID-19 associated sino-orbital mucormycosis]
N V Boiko1, V N Kolesnikov1, A A Khanamirov2
1Rostov State Medical University, Rostov-on-Don, Russia.
Vestnik Otorinolaringologii
|May 15, 2023
Summary
COVID-19 patients with sino-orbital mucormycosis showed symptom progression over time. Clinical forms of this fungal infection indicate invasive spread stages, impacting the sinuses and orbits.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Critical Care Medicine
Context:
- COVID-19 associated mucormycosis is a severe opportunistic infection.
- Patients often have underlying conditions like diabetes mellitus.
- The study focuses on sino-orbital mucormycosis in a hospitalized cohort.
Purpose:
- To analyze the symptom dynamics in patients with COVID-19 associated sino-orbital mucormycosis.
- To classify disease phenotypes based on clinical and CT findings.
- To understand the progression of fungal invasion.
Summary:
- A series of 13 patients with COVID-19 associated sino-orbital mucormycosis were analyzed.
- Patients presented with varying degrees of sino-orbital involvement, including superior orbital fissure and orbital apex syndromes.
- Intracranial spread was observed in some severe cases, indicating rhino-sino-cerebral mucormycosis.
Impact:
- Clinical presentations of mucormycosis correlate with the invasive spread of fungi.
- Understanding symptom dynamics aids in early diagnosis and management of sino-orbital mucormycosis.
- This research highlights the severe complications of mucormycosis in COVID-19 patients.
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