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Polyphenol-assisted assembly of Au-deposited polylactic acid microneedles for SERS sensing and antibacterial
Zi-Chun Chia1, Yi-Lun Chen2, Cheng-Hsun Chuang2
1Department of Photonics, National Cheng Kung University, Tainan 70101, Taiwan.
Chemical Communications (Cambridge, England)
|May 15, 2023
Abstract:
3D SERS microneedles with self-assembled AuNPs were fabricated with tannic acid (chemical glue and reductant) on polylactic acid microneedles for in-depth chemical and biomolecular analysis, with LOD values below 200 ppb for small molecules and 102 CFU cm-2 for bacteria. The MB/Au-microneedles were used for photodynamic therapy with SERS-monitored photosensitizer degradation.
