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Updated: Jul 30, 2025

Manipulation of Single Neural Stem Cells and Neurons in Brain Slices using Robotic Microinjection
Published on: January 21, 2021
In vivo applications of micro/nanorobots
Cagatay M Oral1, Martin Pumera1,2
1Future Energy and Innovation Laboratory, Central European Institute of Technology, Brno University of Technology, Purkynova 123, 61200, Brno, Czech Republic. martin.pumera@ceitec.vutbr.cz.
Abstract:
Untethered robots in the size range of micro/nano-scale offer unprecedented access to hard-to-reach areas of the body. In these challenging environments, autonomous task completion capabilities of micro/nanorobots have been the subject of research in recent years. However, most of the studies have presented preliminary in vitro results that can significantly differ under in vivo settings. Here, we focus on the studies conducted with animal models to reveal the current status of micro/nanorobotic applications in real-world conditions. By a categorization based on target locations, we highlight the main strategies employed in organs and other body parts. We also discuss key challenges that require interest before the successful translation of micro/nanorobots to the clinic.

