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Updated: Jul 30, 2025

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients
02:28

Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients

Published on: March 1, 2024

440

Cardiovascular comorbidity in psoriasis - psoriatic inflammation is more than just skin deep

Katharina S Kommoss1,2, Alexander Enk1, Mathias Heikenwälder2

  • 1Department of Dermatology, University Hospital Heidelberg, Heidelberg, Germany.

Journal Der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG
|May 15, 2023
PubMed

Insights

Psoriasis involves systemic inflammation, increasing cardiovascular risk. Managing comorbidities is crucial for patients, requiring interdisciplinary care to address vascular inflammation and heart disease.

Area of Science:

  • Dermatology
  • Cardiology
  • Immunology

Background:

  • Psoriasis is increasingly understood as a systemic inflammatory condition, not just a skin disease.
  • Guidelines recommend managing comorbidities like metabolic and cardiovascular diseases in psoriasis patients.
  • Psoriasis is now recognized by cardiologists as a risk factor for cardiovascular inflammation.

Purpose of the Study:

  • To review epidemiological, mechanistic, and management aspects of psoriasis and its comorbidities.
  • To contextualize findings for physicians treating psoriasis patients.
  • To highlight interdisciplinary care efforts for vascular inflammation and cardiovascular disease in psoriasis.

Main Methods:

  • Literature review was conducted.
  • Key findings on epidemiology, mechanisms, and management were summarized.

Main Results:

  • Research is ongoing to understand the mechanisms of systemic inflammation in psoriasis.
  • Studies on treating cardiovascular comorbidities with dermatological therapies show mixed results.
  • Diagnosing psoriasis has implications for preventing and treating associated diseases.

Conclusions:

  • Understanding psoriasis comorbidities necessitates interdisciplinary patient care.
  • This article focuses on advancements in managing vascular inflammation and cardiovascular disease in psoriasis patients.
Abstract

Keywords:
Interleukin-17APsoriasiscomorbid diseases in psoriasisvascular inflammation

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