Solid-liquid transition induced by rigidity disparity in a binary mixture of cell tissues
Related Experiment Video
Updated: Jul 30, 2025

Combining Microfluidics and Microrheology to Determine Rheological Properties of Soft Matter during Repeated Phase Transitions
Published on: April 19, 2018
Jia-Jian Li1,2, Yu-Ling He1,2, Bao-Quan Ai1,2
1Guangdong Provincial Key Laboratory of Quantum Engineering and Quantum Materials, School of Physics and Telecommunication Engineering, South China Normal University, Guangzhou 510006, China. 20162321022@m.scnu.edu.cn.
Abstract:
The two-dimensional melting of a binary mixture of cell tissues is numerically investigated in the presence of rigidity disparity. We present the full melting phase diagrams of the system by using the Voronoi-based cellular model. It is found that the enhancement of rigidity disparity can induce a solid-liquid transition at both zero temperature and finite temperature. (i) In the case of zero temperature, the system undergoes a continuous solid-hexatic transition followed by a continuous hexatic-liquid transition for zero rigidity disparity, but a discontinuous hexatic-liquid transition for finite rigidity disparity. Remarkably, the solid-hexatic transitions always arise when the soft cells reach the rigidity transition point of monodisperse systems. (ii) In the case of finite temperature, the melting occurs via a continuous solid-hexatic transition followed by a discontinuous hexatic-liquid transition. Our study may contribute to the understanding of solid-liquid transitions in binary mixture systems with rigidity disparity.
Related Concept Videos
Phase Transitions
Relation between Poisson's ratio, Modulus of Elasticity and Modulus of Rigidity
Molecular Comparison of Gases, Liquids, and Solids
States of Matter and Phase Changes
Tissue Homogenization and Cell Lysis
Mechanical methods of tissue homogenization
These methods rely on applying external physical force to disrupt...
Characteristics of Fluids

