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Updated: Jul 30, 2025

Y-90 Radioembolization and PD-1 Inhibitor as Neoadjuvant Treatment in Hepatocellular Carcinoma
Published on: May 24, 2024
BRAZILIAN SOCIETY OF HEPATOLOGY UPDATED RECOMMENDATIONS FOR SYSTEMIC TREATMENT OF HEPATOCELLULAR CARCINOMA
Aline Lopes Chagas1, Cassia Regina Guedes Leal2, Vivianne Barreto de Mello3
1Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo, Divisão de Gastroenterologia Clínica e Hepatologia, São Paulo, SP, Brasil.
Updated guidelines for hepatocellular carcinoma (HCC) systemic treatment are presented, incorporating recent advancements in drugs and evidence. These recommendations aim to guide healthcare professionals in Brazil and Latin America for optimal HCC patient care.
Area of Science:
- Hepatology
- Oncology
- Clinical Medicine
Background:
- Hepatocellular carcinoma (HCC) is a leading cause of cancer mortality globally.
- Previous Brazilian Society of Hepatology (SBH) recommendations for HCC diagnosis and treatment were published in 2020.
- Recent literature reveals new systemic therapies for HCC not included in prior guidelines.
Conclusions:
- The updated recommendations aim to guide healthcare professionals, policymakers, and planners in Brazil and Latin America.
- These guidelines facilitate informed decision-making for the systemic treatment of patients with HCC.
- The document reflects the latest advancements in HCC systemic therapy, enhancing patient care strategies.
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