Related Experiment Video
Updated: Jul 30, 2025
Constructing Mutants in Serotype 1 Streptococcus pneumoniae strain 519/43
Published on: September 11, 2020
Coverage of 13-Valent Pneumococcal Conjugate Vaccine Among Children 0-15 Months of Age - 9 Provinces, China,
Lijun Liu1, Zhaonan Zhang2, Xixi Zhang2
1Sichuan Center for Disease Control and Prevention, Chengdu City, Sichuan Province, China.
Insights
Coverage of the 13-valent pneumococcal conjugate vaccine (PCV13) in China is low, despite annual increases. Public health strategies are needed to improve PCV13 uptake and reduce regional disparities.
Area of Science:
- Public Health
- Vaccinology
- Epidemiology
Background:
- Limited data exist on the 13-valent pneumococcal conjugate vaccine (PCV13) coverage in China.
- Lack of official statistics and published literature hinders accurate assessment of PCV13's current situation.
Purpose of the Study:
- To investigate the utilization of PCV13 in China.
- To estimate PCV13 coverage in nine provinces between 2019 and 2021.
Main Methods:
- Cross-sectional study design.
- Data collected from nine provinces representing eastern, central, and western China.
- Analysis of PCV13 usage and coverage rates from 2019 to 2021.
Main Results:
- PCV13 usage showed an annual increase from 2019 to 2021.
- Overall PCV13 coverage remained suboptimal across the studied regions.
- Significant vaccination coverage gaps were observed between eastern and western China.
Conclusions:
- Strategies to improve PCV13 uptake are crucial for public health in China.
- Consideration should be given to including PCV13 in the Expanded Program of Immunization.
- Reducing vaccine prices and addressing regional disparities are essential for enhancing PCV13 coverage, especially with domestic vaccine availability.
What Is Already Known On This Topic?:
Limited data exist regarding the coverage of the 13-valent pneumococcal conjugate vaccine (PCV13) in China. A lack of official statistics, coupled with an insufficient body of published literature, hinders the accurate depiction of the current situation.
What Is Added By This Report?:
This study investigated the utilization of PCV13 and estimated its coverage in nine provinces across eastern, central, and western China between 2019 and 2021. Despite an annual increase in PCV13 usage during this period, the overall coverage remained suboptimal.
What Are The Implications For Public Health Practice?:
Consideration should be given to incorporating vaccines into the Expanded Program of Immunization, reducing vaccine prices, and addressing the vaccination coverage gap between eastern and western regions when there is an adequate supply of PCV13, particularly with domestic vaccines.
Related Concept Videos
02:50Conjugated Proteins
Nucleoproteins are protein complexes that contain nucleic acids, categorized as deoxyribonucleoproteins (DNPs) or ribonucleoproteins (RNPs) respectively. The nucleosome is a typical example of a DNP where nuclear DNA is associated with histone proteins. The major antigen for the Covid-19 virus SARS-CoV is an RNP that is critical...
01:51Vaccinations
01:30Pneumonia V: Nursing management and Prevention
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
01:30Pneumonia III: Complications and Assessment