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Intracranial Extra-axial Undifferentiated Pleomorphic Sarcoma; a Case Report.

Muhammad Omer Altaf1, Saad Khalil Chaudhry1, Palwasha Gul1

  • 1Department of Radiology, Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, Pakistan.

Journal of Cancer & Allied Specialties
|May 17, 2023
PubMed
Summary
This summary is machine-generated.

Undifferentiated pleomorphic sarcoma (UPS), a rare intracranial tumor, was diagnosed in a young male presenting with vision loss and headache. Surgical resection and follow-up confirmed successful treatment, highlighting the importance of early diagnosis and management of these rare brain tumors.

Keywords:
Case reporthead-and-neck cancersarcomaundifferentiated pleomorphic sarcoma

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Area of Science:

  • Neuro-oncology
  • Soft-tissue sarcoma research
  • Medical imaging in oncology

Background:

  • Head-and-neck sarcomas are aggressive malignancies with high mortality rates.
  • Undifferentiated pleomorphic sarcoma (UPS) is a high-grade soft-tissue tumor typically found in limbs and retroperitoneal cavities.
  • Intracranial soft-tissue sarcomas are rare but can occur as primary lesions within the brain.

Observation:

  • A young male presented with occipital headache and blurred vision.
  • Imaging revealed an extra-axial intracranial mass with specific characteristics on CT and MRI.
  • Histopathology confirmed the diagnosis of UPS after surgical excision.

Findings:

  • The patient underwent successful surgical resection of the intracranial UPS.
  • Post-operative imaging showed no residual disease.
  • The patient remained asymptomatic for over two years post-surgery.

Implications:

  • Differentiating intracranial soft-tissue sarcomas from other extra-axial tumors requires understanding clinical and radiological features.
  • Surgical excision, radiotherapy, and regular follow-ups are crucial for managing intracranial sarcomas.
  • Prompt tissue sampling and staging scans are essential for accurate diagnosis and treatment planning.