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2021-2022 Drug Updates in Solid Tumors
1From M Health Fairview and Mayo Clinic College of Medicine, Maple Grove, Minnesota.
Abstract:
During JADPRO Live 2022, Kirollos Hanna, PharmD, BCPS, BCOP, briefed advanced practitioners on key FDA approvals from late 2021 to late 2022. He described mechanisms of action that are unique across some malignancies, as well as mechanisms of action that clinicians can utilize through an expanded indication or across other solid malignancies. Finally, he discussed safety profiles and what advanced practitioners can and should do in monitoring across solid tumors.
Insights
Advanced practitioners received updates on key FDA-approved oncology drugs from late 2021 to late 2022. The review covered novel mechanisms of action, expanded indications, and safety monitoring strategies for solid tumors.
Area of Science:
- Oncology
- Pharmacology
- Clinical Practice
Background:
- The landscape of cancer therapeutics is rapidly evolving with frequent regulatory approvals.
- Advanced practitioners require timely updates on new treatments to optimize patient care.
Purpose of the Study:
- To summarize significant Food and Drug Administration (FDA) approvals in oncology from late 2021 to late 2022.
- To discuss the mechanisms of action, clinical utility, and safety profiles of newly approved agents.
- To provide guidance on monitoring strategies for advanced practitioners managing patients with solid tumors.
Main Methods:
- Review of key FDA oncology drug approvals.
- Discussion of unique and expanded mechanisms of action.
- Analysis of safety profiles and monitoring recommendations.
Main Results:
- Key FDA approvals in oncology were presented.
- Mechanisms of action, including unique and transferable ones across malignancies, were detailed.
- Safety profiles and essential monitoring practices for advanced practitioners were outlined.
Conclusions:
- Advanced practitioners were updated on critical late 2021-2022 FDA oncology approvals.
- Understanding novel mechanisms of action and safety is crucial for effective treatment.
- Proactive monitoring is essential for optimizing outcomes in patients with solid tumors.
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