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Related Concept Videos

Microbial Biosensors01:17

Microbial Biosensors

Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...

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A green cellulose nanofiber-based printed electrode for practical highly sensitive amoxicillin detection.

Shaimah Rinda Sari1, Erika Shinchi2, Kenji Shida3

  • 1Graduate School of Science and Engineering, Saga University, 1 Honjomachi, Saga 840-8502, Japan. masato@cc.saga-u.ac.jp.

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A new single-use electrode made from cellulose nanofibers (CNFs) offers sensitive detection of the antibiotic amoxicillin (AMX) in water. This biodegradable sensor provides a cost-effective and eco-friendly solution for water quality monitoring.

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Area of Science:

  • Electrochemistry
  • Materials Science
  • Environmental Science

Background:

  • Simple electrochemical detection of amoxicillin (AMX) is vital for mitigating health and environmental risks.
  • Current methods often rely on single-use electrodes, leading to increased waste and costs.
  • Biodegradable cellulose nanofibers (CNFs) offer a sustainable alternative for electrode fabrication.

Purpose of the Study:

  • To develop a sensitive, single-use, and cost-effective electrode for amoxicillin detection in water.
  • To utilize cellulose nanofibers (CNFs) as a biodegradable framework for printed electrodes.
  • To investigate the electrochemical behavior and practical applicability of the developed sensor.

Main Methods:

  • Fabrication of a single-use CNF-based printed electrode.
  • Modification of the electrode with polybenzimidazole (PBI)-wrapped multi-walled carbon nanotubes (MWCNTs).
  • Electrochemical characterization and determination of amoxicillin in water samples (seawater and tap water).

Main Results:

  • The CNF-based printed electrode achieved a low detection limit of 0.3 μM for AMX.
  • A wide detection range of 0.3–500 μM was observed, surpassing previous studies.
  • Electrode reactions were identified as primarily involving adsorbed species at low concentrations and diffusion-controlled at high concentrations.
  • Successful determination of AMX in real water samples (seawater and tap water) using a simple soaking method and calibration equations.

Conclusions:

  • The developed CNF-based printed electrode offers a sensitive and practical method for amoxicillin detection.
  • The use of biodegradable CNFs and MWCNTs provides an eco-friendly and potentially cost-effective sensor platform.
  • This electrode shows significant potential for real-time, field-based monitoring of amoxicillin in aquatic environments.